Charles D Meyers Selected Research

Diacylglycerol O-Acyltransferase

1/2017	Discovery of an Orally Bioavailable Benzimidazole Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor That Suppresses Body Weight Gain in Diet-Induced Obese Dogs and Postprandial Triglycerides in Humans.
11/2016	Effect of Pradigastat, a Diacylglycerol Acyltransferase 1 Inhibitor, on the QTcF Interval in Humans.
10/2015	Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor.
9/2015	Pharmacokinetics, pharmacodynamics, safety, and tolerability of pradigastat, a novel diacylglycerol acyltransferase 1 inhibitor in overweight or obese, but otherwise healthy human subjects.

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Charles D Meyers Research Topics

Disease

3	Hyperlipoproteinemia Type I (Lipoprotein Lipase Deficiency, Familial) 12/2017 - 10/2015
2	Body Weight (Weight, Body) 01/2019 - 01/2017
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Diarrhea 01/2019
1	Flatulence 01/2019
1	Obesity 01/2019
1	Weight Loss (Weight Reduction) 01/2019
1	Abdominal Pain (Pain, Abdominal) 01/2019
1	Costello Syndrome 12/2017
1	Overweight 09/2015
1	Diabetes Mellitus 07/2006

Drug/Important Bio-Agent (IBA)

4	Diacylglycerol O-AcyltransferaseIBA 01/2017 - 09/2015
3	pradigastatIBA 11/2016 - 09/2015
2	Triglycerides (Triacylglycerol)IBA 12/2017 - 01/2017
1	Glucagon (Glukagon)FDA Link 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	Hormones (Hormone)IBA 01/2019
1	Insulin (Novolin)FDA Link 01/2019
1	licogliflozinIBA 01/2019
1	SodiumIBA 01/2019
1	SymportersIBA 01/2019
1	IncretinsIBA 01/2019
1	DiglyceridesIBA 12/2017
1	benzimidazoleIBA 01/2017
1	LipidsIBA 07/2006